Rugger-jersey spine in osteopetrosis

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A Case of Cavernous Sinus Thrombophlebitis and Meningitis as a Complication in Osteopetrosis

Osteopetrosis is a rare genetic bone disease characterized by increased bone density but prone to breakage due to defective osteoclastic function. Among two primary types of autosomal dominant osteopetrosis (ADO), osteopetrosis type II is characterized by sclerosis of bones, predominantly involving the spine, the pelvis, and the skull base. Fragility of bones and dental abscess are leading comp...

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Osteopetrosis

Osteopetrosis ("marble bone disease") is a descriptive term that refers to a group of rare, heritable disorders of the skeleton characterized by increased bone density on radiographs. The overall incidence of these conditions is difficult to estimate but autosomal recessive osteopetrosis (ARO) has an incidence of 1 in 250,000 births, and autosomal dominant osteopetrosis (ADO) has an incidence o...

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[Spondylolysis in osteopetrosis].

We report the occurrence of spondylolysis and/or spondylolisthesis of the lumbar vertebrae in five patients with osteopetrosis, four of them having multiple lesions. The case histories indicate that spondylolysis had developed in the pathological bone as a result of increased stress and that it is an acquired lesion.

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Haemolytic Anaemia in Osteopetrosis

The anaemia so frequently found in cases of osteopetrosis in children has been generally regarded as being due to poor development of the bone marrow cavity by failure of absorption and organization of primitive chondro-osteoid tissue (Warkany, 1959; Clifton and Frank, 1959; Aegerter and Kirkpatrick, 1958). In many cases, however, the severity of the anaemia has not corresponded with the radiol...

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Osteopetrosis in Successive Generations

Case 1. A full-term male child, weighing 6j lb., the product of a second pregnancy, was born on Aug. 3, 1945. The parents were unrelated. When three months old the child was thought to be blind, and two months later on x-ray examination a diagnosis of osteopetrosis was made. Mental retardation was noted at ten months. At two years two months he was admitted to the Royal Blind School; he was a w...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2017

ISSN: 1757-790X

DOI: 10.1136/bcr-2017-220275